In the battle against chronic diseases, the role of lifestyle choices has taken centre stage. Chronic illnesses, a major global health concern, contribute significantly to worldwide mortality rates. Researchers have now shed light on the substantial impact that maintaining a healthy diet, regular physical activity, and adequate sleep can have on preventing chronic non-communicable diseases. With the burden of chronic diseases driven by unhealthy lifestyles, environmental factors, and increasing life expectancy in Western nations, the importance of adopting these healthy habits cannot be overstated.
Chronic diseases not only result in poor health, disabilities, and premature death but also place a significant strain on healthcare resources. In Western societies, these conditions are often attributed to hazardous lifestyles, environmental influences, and a longer lifespan.
In a recent editorial published in Nutrients, researchers emphasized the critical role of a balanced diet, regular physical activity, and sufficient sleep in the prevention of chronic non-communicable diseases.
A holistic approach to healthy living, encompassing nutritious eating, frequent exercise, and ample rest, can substantially delay or even avert the onset of chronic diseases. However, the importance of sleep, a pillar of overall health, is being eroded as people's typical sleep durations decrease while the prevalence of sleep disorders increases.
Sleep significantly affects appetite and dietary choices, with reduced sleep leading to increased feelings of hunger, appetite, and food consumption. Integrating timing considerations into lifestyle interventions can yield additional health benefits and enhance adherence. Prior studies have shown that sleep deprivation elevates levels of the hunger hormone ghrelin, particularly in the late evening hours.
It is noteworthy that weight reduction strategies have a substantial impact on both cardiometabolic health and sleep quality. The timing of sleep phases also plays a crucial role in appetite and hunger management, underscoring the metabolic importance of regulating sleep according to circadian rhythms. Social jetlag, characterized by differences in sleep hours between weekdays and weekends, is associated with adverse metabolic health outcomes.
Research reveals that individuals with early-morning tendencies tend to consume diets rich in fibre, potassium, phosphorus, magnesium, and vitamin K, while also reducing their intake of carbohydrates, proteins, total lipids, salt, and saturated fatty acids, particularly during dinner. The relationship between dietary habits and type 2 diabetes risk has also been established, with healthy eating patterns linked to a reduced risk among adults, albeit with gender differences.
Moreover, lifestyle habits exert a profound influence on metabolic diseases and even cancers. Tumor cells adapt unique metabolic profiles as diseases progress, rendering them highly sensitive to alterations in food sources and overall metabolic status. As a result, dietary treatments have garnered increased attention from cancer researchers and oncologists.
For instance, dietary habits and intestinal microbiota composition significantly affect the risk of colorectal cancer (CRC). A study conducted among Han Chinese participants found that healthy diets featuring dairy products, fruits, and vegetables reduced the risk of CRC in specific enterotypes of the intestinal microbiota.
Furthermore, lifestyle interventions have shown the highest efficacy in managing metabolic dysfunction-associated steatotic liver disease (MASLD), a widespread metabolic disorder. A year-long study demonstrated the positive impact of Mediterranean diets and physical exercise on glucose metabolism trajectories in MASLD patients.
In a different study, researchers explored the connection between behavioural patterns and MASLD among overweight or obese individuals. The findings showed a lower incidence of MASLD among individuals with high activity amplitudes and favourable feeding rhythms. These connections were particularly robust among obese individuals, highlighting the potential for behavioural therapies in MASLD management.